PRN De3 Dry Eye Omega Benefits: The Complete Canadian Guide
Quick answer: PRN De3 Dry Eye Omega Benefits is one of Canada's most purpose-built oral omega-3 formulas for dry eye. Its three-softgel daily serving provides 1,680 mg EPA, 560 mg DHA and 1,000 IU vitamin D3. The 3:1 EPA:DHA blend is supplied in re-esterified triglyceride (rTG) form, and Health Canada has licensed specific claims related to dry-eye signs and symptoms associated with meibomian gland dysfunction. Those strengths make it a top-tier option, although omega-3 research remains mixed and no supplement is universally best for every person.
Not every fish-oil bottle is designed with dry eye in mind. Some provide only a few hundred milligrams of EPA and DHA, some emphasize DHA rather than EPA, and others do not identify the chemical form of the oil. PRN De3 Dry Eye Omega Benefits stands out because the dose, ratio, rTG form and Canadian product licence all point toward a very specific use case.
This guide explains what is inside PRN De3, why it is frequently recommended by eye-care professionals, what the research can and cannot prove, and how the coming EyePromise name change fits into the Canadian story.
What is PRN De3 Dry Eye Omega Benefits?
PRN De3 is an oral natural health product for adults. Rather than coating the ocular surface like an eye drop, it supplies long-chain omega-3 fatty acids and vitamin D3 systemically. Health Canada's Natural Health Product Licence Database lists it under NPN 80101489.
The licensed Canadian directions are three capsules once daily. That serving supplies the following:
| Ingredient | Daily amount | Why shoppers examine it |
|---|---|---|
| EPA | 1,680 mg | The dominant omega-3 in the formula; the high EPA percentage is a distinguishing feature of the 3:1 blend. |
| DHA | 560 mg | A long-chain omega-3 found in ocular and neural tissues; it complements EPA rather than replacing it. |
| Vitamin D3 | 1,000 IU (25 mcg) | Supports immune function and bone health under the Canadian licence; vitamin D status is also being studied in dry eye. |
The total labelled EPA plus DHA is 2,240 mg per day. The formula also contains additional omega-3 fatty acids, with fish oil sourced from species such as anchovy, sardine and mackerel. The capsules contain bovine gelatin and a soy-derived mixed tocopherol, so the product is not vegetarian and may not suit every allergy profile.
Why is PRN De3 considered a top dry-eye omega?
“Top” should mean more than expensive packaging or a large fish-oil number on the front label. A serious comparison should examine the amount of EPA and DHA—not merely total fish oil—the ratio between them, the oil form, the serving burden, the quality controls and the claims the Canadian regulator has authorized.
PRN De3 performs strongly on that checklist:
- High active dose: 2,240 mg of EPA plus DHA in three capsules.
- Deliberate 3:1 EPA:DHA ratio: a high-EPA profile rather than a general wellness blend.
- Re-esterified triglyceride form: an absorbable form that has shown stronger long-term incorporation than ethyl esters in some comparative research.
- Vitamin D3 included: 1,000 IU per daily serving.
- Dry-eye-specific Canadian licence: the NPN entry includes claims involving OSDI symptom scores, tear osmolarity, tear break-up time and MMP-9 in dry eye associated with meibomian gland dysfunction.
- Three-softgel routine: a concentrated format available in 30-, 60- and 90-day bottle sizes.
That combination makes PRN De3 one of the most complete dry-eye omega formulas available through EyeDropShop. It does not mean that every person will respond, that it replaces an eye exam, or that a less expensive formula cannot be appropriate. For a closer look at the numbers, read why PRN De3 uses a 3:1 EPA:DHA ratio.
What does the Health Canada licence actually say?
The NPN is especially important because it separates authorized Canadian wording from broader marketing language used in other countries. The current licence states that De3 helps improve signs and relieve symptoms of dry eyes associated with meibomian gland dysfunction, including improvements measured by OSDI, tear osmolarity and tear break-up time. It also references MMP-9, an inflammatory marker in the tear film.
This does not turn a supplement into a cure or guarantee a result. It means Health Canada reviewed evidence supporting the approved conditions of use. Consumers should still follow the Canadian label and discuss persistent symptoms with an optometrist or ophthalmologist.
What is rTG omega-3?
Concentrated fish oil is often converted into an ethyl ester form during processing. In an rTG product, the fatty acids are reattached to a glycerol backbone after concentration and purification. The result is a re-esterified triglyceride structure.
A six-month randomized comparison found a larger rise in the omega-3 index with re-esterified triglycerides than with an equal dose in ethyl ester form. That supports the practical importance of form, but it does not establish a universal “three times better” rule for every product, meal and person. Bioavailability varies with formulation and whether capsules are taken with food containing fat.
What do clinical trials show?
The evidence deserves a balanced answer. A 2016 randomized trial studied the same 1,680 mg EPA and 560 mg DHA rTG dose in people with dry eye related to meibomian gland dysfunction. After 12 weeks, the omega-3 group improved more than safflower-oil control on tear osmolarity, tear break-up time, OSDI scores and MMP-9.
However, the large 2018 DREAM trial tested a different omega-3 regimen—2,000 mg EPA and 1,000 mg DHA in ethyl ester form—and found no meaningful advantage over an olive-oil placebo after one year. More recently, a 2024 randomized trial using De3 at 1,680 mg EPA and 560 mg DHA did not find a symptom advantage over grapeseed oil after 12 weeks in a smaller MGD population.
Meanwhile, a 2023 meta-analysis of randomized trials reported overall improvements and found that higher dose, longer duration and higher EPA percentage were associated with greater symptom reduction. The studies differed greatly in formulation, populations and controls, which is one reason conclusions remain inconsistent.
Evidence in context: PRN De3 has a well-specified, clinically studied formula and Health Canada-authorized dry-eye claims. The total body of omega-3 evidence is still mixed. It is more accurate to call it a leading formula on dose, form and regulatory positioning than to promise that it is proven superior for everyone.
How long should you try it?
Omega-3 supplements are not fast-acting lubricating drops. The current directions recommend daily, consistent use, and the brand advises allowing about 90 days to evaluate a response. Taking it sporadically for a week is unlikely to be a useful test.
Use the full labelled serving unless a healthcare professional advises otherwise, take it with a meal, and track symptoms using the same questions over time: burning, grittiness, end-of-day comfort, contact-lens tolerance and reliance on rescue drops. Our PRN De3 dosage and safety guide explains how to run a sensible 90-day trial.
Who should ask a healthcare professional first?
Ask before starting if you take anticoagulant or antiplatelet medication, have a bleeding disorder, are preparing for surgery, are pregnant or breastfeeding, have a fish or soy allergy, take other vitamin D products or have a condition affected by vitamin D or calcium. Health Canada's record specifically advises consultation during pregnancy or breastfeeding and if dry-eye symptoms persist or worsen.
New pain, significant redness, discharge, injury, light sensitivity or a sudden change in vision should be assessed rather than managed with a supplement trial.
Is PRN De3 becoming EyePromise De3?
Yes—in the United States, De3 has moved to EyePromise branding with “new look, same formula” messaging. PRN Vision Group, EyePromise and Avenova have been brought together under the EyePromise identity. Canadian stock is still sold as PRN De3 at the time of writing.
Frequently asked questions
Is PRN De3 a medication?
It is a licensed Canadian natural health product, not a prescription dry-eye medication. It should complement—not replace—diagnosis and a complete dry-eye plan.
Can I take fewer than three softgels?
Three daily is the licensed adult dose and the amount that delivers the stated formula. Ask your healthcare professional before changing it.
Does it replace warm compresses or eye drops?
No. Dry eye is multifactorial. Omega-3 may be one part of a plan that also addresses eyelids, meibomian glands, tear replacement, environment and prescription treatment when needed.
Explore PRN De3 in Canada
View product details
View product details
Sources
- EyeDropShop Canada: PRN De3 product page
- Health Canada Natural Health Product Licence Database: NPN 80101489
- EyePromise: De3 Omega Benefits
- Epitropoulos et al., 2016
- DREAM Research Group, 2018
- JAMA Ophthalmology randomized trial, 2024
- Wang and Ko meta-analysis, 2023
- Neubronner et al.: rTG versus ethyl ester incorporation
This article is educational and does not replace advice from an optometrist, ophthalmologist, pharmacist or physician. Product formulas and packaging can change; check the current Canadian label.
Does PRN De3 Work for Dry Eye? A Balanced Look at the Research
Quick answer: PRN De3's 1,680 mg EPA/560 mg DHA rTG formula has produced encouraging results in one randomized dry-eye trial, but a later randomized trial using De3 found no symptom advantage over grapeseed oil. The large DREAM trial also found no benefit for a different ethyl-ester omega-3 formula over olive-oil placebo. Meta-analyses suggest omega-3 may help some patients, especially with higher doses, longer duration and higher EPA percentage, but the evidence is heterogeneous. PRN De3 is a strong, well-studied formula—not a guaranteed cure.
Authority is built by explaining the inconvenient studies as carefully as the favourable ones. Omega-3 for dry eye is a good example: credible trials point in different directions.
This article separates product-specific evidence from broad omega-3 evidence and explains why study design, oil form, placebo choice and dry-eye subtype can change the answer.
The 2016 PRN-formula trial: positive results
Epitropoulos and colleagues randomized 105 adults with dry eye and meibomian gland dysfunction to four daily softgels providing 1,680 mg EPA and 560 mg DHA in rTG form, or safflower-oil control, for 12 weeks. The active group showed greater improvement in tear osmolarity, tear break-up time, OSDI symptom scores and MMP-9.
This study matters because the EPA:DHA amounts and rTG form closely match PRN De3. It also aligns with the outcomes named in Health Canada's licence. Limitations include modest size, 12-week duration, and author disclosures involving the product company.
The DREAM trial: no advantage over placebo
The 2018 DREAM trial enrolled 535 people at 27 sites. Participants received 2,000 mg EPA plus 1,000 mg DHA in ethyl ester form or an olive-oil placebo. After one year, both groups improved, but omega-3 was not significantly better for symptoms or common clinical signs.
DREAM is larger and highly influential. It should prevent categorical statements that “omega-3 is proven to treat dry eye.” It did not test PRN De3's precise ratio, rTG form or vitamin D3, but it did test a substantial marine omega-3 dose in typical moderate-to-severe dry eye.
The 2024 De3 trial: a formula-specific negative result
A 2024 randomized clinical trial focused on dry eye associated with meibomian gland dysfunction. The omega-3 group received De3 at 1,680 mg EPA and 560 mg DHA daily; the control group received 3,000 mg grapeseed oil. Fewer than 60 participants were evaluated per group, and the study did not show a symptom benefit for De3 over control at 12 weeks.
This study is especially relevant because it used the branded formula. It does not erase the 2016 findings, but it means marketing should never present the earlier trial as the final answer.
| Study | Formula/control | Duration | Main takeaway |
|---|---|---|---|
| 2016 Epitropoulos | 1,680 EPA/560 DHA rTG vs safflower oil | 12 weeks | Favoured omega-3 on several signs and symptoms |
| 2018 DREAM | 2,000 EPA/1,000 DHA ethyl ester vs olive oil | 12 months | No meaningful advantage over control |
| 2024 MGD trial | De3 1,680 EPA/560 DHA vs grapeseed oil | 12 weeks | No symptom advantage over control |
Why can good trials disagree?
- Dry eye is not one condition. Aqueous deficiency, MGD, allergy, neuropathic pain and environmental stress can produce overlapping symptoms.
- Controls may not be inert. Olive, safflower and grapeseed oils have different fatty acids and biological effects.
- Formulations differ. Dose, EPA percentage, rTG versus ethyl ester, vitamin D and capsule schedule vary.
- Background treatment differs. Some studies allow participants to continue other dry-eye therapies.
- Symptoms fluctuate. Weather, screens, adherence and regression to the mean can influence outcomes.
- Outcome measures disagree. Symptoms and clinical signs often correlate poorly in dry eye.
Why is PRN De3 still a leading option?
If a Canadian adult and their eye-care professional decide an omega-3 use is advisable, PRN De3 offers unusually clear specifications: 2,240 mg EPA+DHA, a 3:1 EPA:DHA ratio, rTG form, vitamin D3, third-party quality positioning and an active Health Canada licence with MGD-related dry-eye claims.
That makes it a strong, rational, evidence-informed choice among supplements. Read how its formula compares with I-VU, NutraSea, Systane and Blink.
How should you judge your own trial?
Agree on a defined window—often 90 days—and keep other major variables as stable as practical. Track symptoms and function rather than waiting for a vague feeling: burning, grittiness, comfortable screen time, contact-lens tolerance, morning comfort and frequency of rescue drops. An eye-care professional can repeat tear break-up time, osmolarity, staining or gland assessment when appropriate.
If there is no meaningful improvement, revisit the diagnosis and the rest of the treatment plan. See how to structure a PRN De3 90-day trial.
Frequently asked questions
Was PRN De3 clinically studied?
Yes. Its 1,680 mg EPA/560 mg DHA rTG formula has been used in randomized trials, including both a positive 2016 study and a negative 2024 study.
Does DREAM prove all omega-3s fail?
No. It found no benefit for its tested ethyl-ester regimen over olive oil in its population. It is strong evidence against universal claims, not proof that every formula fails every subgroup.
Can Health Canada authorize claims when studies are mixed?
Yes. A product licence reflects evidence reviewed for specific conditions of use. It does not mean every future trial will be positive or that the result is guaranteed.
Review PRN De3 product details
See the Canadian formula and sizes
See the Canadian formula and sizes
Sources
- Epitropoulos et al., 2016
- DREAM Research Group, 2018
- Randomized De3 MGD trial, 2024
- Cochrane review, 2019
- Wang and Ko meta-analysis, 2023
- Health Canada NPN 80101489
This evidence summary is educational and does not provide individual medical advice.
How to Take PRN De3: Dosage, 90-Day Trial, Safety & Side Effects
Quick answer: The Canadian licensed dose of PRN De3 is three softgels once daily for adults 18 and older. Take them consistently with a meal and allow roughly 90 days to judge the result. Ask a healthcare professional first if you use blood thinners, have a bleeding disorder or fish/soy allergy, are pregnant or breastfeeding, are preparing for surgery, or already take vitamin D. Do not exceed the label or use the supplement to delay assessment of worsening eye symptoms.
A premium formula can only be evaluated if the routine is consistent. PRN De3 supplies its stated 1,680 mg EPA, 560 mg DHA and 1,000 IU vitamin D3 at the full three-softgel daily serving.
What is the recommended dose?
Health Canada's licence lists three capsules once daily for adults 19 and older. The EyeDropShop product is available in 90, 180 and 270 softgels, corresponding to approximately 30, 60 and 90 days at the labelled dose.
| Bottle size | Approximate duration |
|---|---|
| 90 softgels | 30 days |
| 180 softgels | 60 days |
| 270 softgels | 90 days |
Should you take all three together?
The Canadian direction is three once daily. Taking them with a meal is practical because dietary fat supports digestion of fat-soluble nutrients and often improves fish-oil tolerability. Choose a meal you eat reliably.
If three capsules at once cause reflux or nausea, ask a pharmacist or clinician whether splitting the dose is appropriate. Do not improvise a permanently lower dose and assume you are receiving the studied formula.
Why use a 90-day trial?
Oral omega-3 does not work like a drop. Incorporation into blood lipids and tissues takes time, and dry-eye trials commonly run for 8 to 12 weeks or longer. PRN currently advises allowing at least 90 days, although some users may notice a change sooner.
A structured trial should have a start date, consistent dose, stable background routine and a review date. Record a weekly 0–10 score for burning, grittiness, end-of-day comfort, screen tolerance and rescue-drop frequency. If possible, pair symptom tracking with an eye-care follow-up.
What side effects can occur?
Fish-oil supplements may cause fishy aftertaste, burping, reflux, nausea, loose stool or abdominal discomfort. Taking capsules with a meal, storing them as directed and avoiding bedtime dosing may help. Stop and seek advice for allergic symptoms or unusual bleeding.
The Canadian product contains fish oil, bovine gelatin and soy-derived mixed tocopherols. Read the current package if you have food allergies or dietary restrictions.
Who should check before starting?
- People taking anticoagulants, antiplatelet drugs or other medicines affecting bleeding.
- People with a bleeding disorder or upcoming surgery/dental procedure.
- Anyone with fish, seafood, soy or capsule-ingredient allergy.
- People who are pregnant or breastfeeding.
- People taking vitamin D, calcium or multiple eye-health supplements.
- Those with kidney disease, high calcium or another condition affected by vitamin D.
- Anyone under 19, because the licensed dose is for adults.
Medication review matters: “Natural” does not mean interaction-free. Bring the bottle or a photo of the medicinal and non-medicinal ingredients to your pharmacist.
Can you take PRN De3 with dry-eye drops?
Omega-3 and lubricating drops work in different ways and are often used in the same overall plan. PRN De3 does not replace preservative-free tears, warm compresses, lid hygiene, environmental changes or prescription treatment when those are indicated.
Dry eye has many causes. If symptoms are primarily allergic, medication-related, aqueous-deficient or neuropathic, omega-3 alone may not address the main driver.
When should you stop the trial?
Stop and obtain advice for a suspected allergy, significant gastrointestinal effects, easy bruising or bleeding, or a new medication interaction. If there is no meaningful eye benefit after a consistent 90-day trial, review the plan rather than continuing indefinitely by habit.
Seek prompt eye care for pain, sudden vision change, injury, discharge, marked light sensitivity or one-sided severe redness. A supplement is not an emergency treatment.
How do you avoid double-counting vitamin D?
PRN De3 supplies 1,000 IU (25 mcg) daily. Add vitamin D from multivitamins, standalone D3, calcium combinations and other eye formulas. Your clinician can advise whether the total fits your needs and whether testing is appropriate.
A simple 90-day checklist
- Confirm suitability with a pharmacist or clinician.
- Record baseline symptoms and current treatments.
- Take three softgels daily with the same meal.
- Keep other major treatment changes to a minimum unless medically necessary.
- Track weekly comfort and functional measures.
- Review at 12 weeks: better, unchanged or worse?
- Continue only if benefit, tolerability, cost and professional advice support it.
Frequently asked questions
Can I take one softgel three times daily?
The licence says three capsules once daily. Ask your eye care practitioner before changing the schedule for tolerability.
What if I miss a day?
Resume the regular labelled schedule. Do not double the next dose unless a healthcare professional instructs you.
Should it be refrigerated?
Follow the storage directions on the current Canadian bottle. Keep it sealed, away from heat, light and children's reach.
Can I judge it after one bottle?
A 90-count bottle lasts about 30 days, which may be too short for a fair trial. The brand recommends about 90 days.
Choose your PRN De3 supply
View 30-, 60- and 90-day sizes
View 30-, 60- and 90-day sizes
Sources
This article provides general education, not individualized medical or pharmaceutical advice.
PRN De3 vs I-VU, NutraSea, Systane & Blink: Which Dry Eye Supplement Stands Out?
Quick answer: PRN De3 stands out among Canadian dry-eye supplements for its 2,240 mg EPA+DHA dose, 3:1 EPA:DHA ratio, rTG form, 1,000 IU vitamin D3 and specific Health Canada dry-eye licence. I-VU Omega-3 Plus offers a lower-cost-looking two-capsule rTG alternative with EPA, DHA and DPA; NutraSea combines triglyceride omega-3 with GLA; Systane uses a 2:1 triglyceride formula; Blink NutriTears is a one-capsule, omega-3-free nutritional approach. “Best” depends on whether the priority is the strongest dry-eye omega specification, fewer capsules, GLA, a non-fish-oil formula or cost.
Comparing supplements by bottle size or “1,000 mg fish oil” can be misleading. The meaningful figures are the full daily EPA and DHA dose, oil form, added nutrients, number of capsules and authorized use.
The table below uses current Canadian EyeDropShop product information. Formulas can change, so confirm the label before purchasing.
| Product | Daily EPA/DHA | Form and extras | Daily serving | Best fit to discuss |
|---|---|---|---|---|
| PRN De3 | 1,680 mg EPA 560 mg DHA 2,240 mg total |
rTG; 1,000 IU D3; 3:1 ratio | 3 softgels | High-dose, dry-eye-specific omega formula with detailed Canadian claims |
| I-VU Omega-3 Plus | 1,200 mg EPA 600 mg DHA 24 mg DPA |
rTG; vitamin E; 2:1 EPA:DHA | 2 softgels | Concentrated rTG omega with fewer capsules and DPA |
| NutraSea Dry Eye | 1,200 mg EPA 300 mg DHA |
Triglyceride; 150 mg GLA; 4:1 ratio | 4 softgels | Omega-3 plus omega-6 GLA strategy |
| Systane Omega-3 | 1,200 mg EPA 600 mg DHA |
Triglyceride; 2:1 ratio | 3 softgels | Straightforward high-potency EPA/DHA formula |
| Blink NutriTears | No EPA or DHA listed | D3, lutein, zeaxanthin, curcuminoids | 1 softgel | One-capsule, non-omega nutritional formula |
Why PRN De3 earns the “top dry-eye omega” position
PRN De3 is not the winner of every possible category. It is the strongest all-around omega-3 choice in this group when the decision is based on a combination of high EPA+DHA dose, rTG form, dry-eye-specific clinical history, vitamin D3 and Health Canada-authorized MGD-related claims.
Its 1,680 mg EPA is higher than the compared omega products, and its combined 2,240 mg EPA+DHA is also the highest. The formula matches the dose used in published randomized dry-eye studies. These are substantive differences, not simply brand prestige.
PRN De3 vs I-VU Omega-3 Plus
Both use re-esterified triglyceride omega-3, which makes this the closest format comparison. I-VU provides 1,200 mg EPA, 600 mg DHA and 24 mg DPA in two capsules. PRN provides 480 mg more EPA, 40 mg less DHA and adds 1,000 IU vitamin D3 in three capsules.
Choose the conversation based on priorities. PRN has the larger EPA+DHA dose, the 3:1 profile and more directly product-matched dry-eye evidence. I-VU has a simpler two-capsule routine, includes DPA and may appeal to someone who already receives enough vitamin D elsewhere.
PRN De3 vs NutraSea Dry Eye
NutraSea uses triglyceride-form omega-3 with 1,200 mg EPA, 300 mg DHA and 150 mg GLA from evening primrose/borage sources. Its 4:1 EPA:DHA ratio is even more EPA-dominant than PRN, but the total EPA+DHA dose is lower and the serving is four softgels.
GLA makes NutraSea a different strategy, not a weaker copy. Someone seeking an omega-3-plus-GLA formula may prefer it. PRN remains the more concentrated EPA+DHA choice and includes D3 rather than GLA.
PRN De3 vs Systane Omega-3
Systane provides 400 mg EPA and 200 mg DHA per softgel, taken three times daily: 1,200 mg EPA plus 600 mg DHA. It uses triglyceride form and has Health Canada dry-eye wording on the Canadian product description.
PRN delivers 440 mg more combined EPA+DHA per day, uses rTG, has a higher EPA percentage and includes D3. Systane offers a clean two-ingredient marine-oil approach without added D3.
PRN De3 vs Blink NutriTears
Blink NutriTears is not an omega-3 competitor in the literal sense. Its one-softgel formula lists vitamin D, lutein, zeaxanthin and curcuminoids, but no EPA or DHA. It targets dry-eye nutrition through a different ingredient set and dramatically lower capsule burden.
For a shopper specifically seeking high-dose EPA/DHA, PRN is the clear fit. For someone unable or unwilling to take fish oil, Blink is a separate category worth discussing. Fish allergy still requires professional guidance; “fish-free” should be verified on the current label.
What about generic fish oil?
A generic can be high quality, but compare active ingredients. A label that says “1,000 mg fish oil” may provide only about 300 mg EPA+DHA. Matching PRN's 2,240 mg could require many capsules. Also check whether the oil is triglyceride, rTG or ethyl ester and whether independent purity data are available.
Price per bottle is therefore less informative than price per 1,000 mg EPA+DHA at the intended daily serving. Even then, a cheaper equivalent should match form, tolerability and quality—not just milligrams.
Which product is right for which priority?
- Highest combined EPA+DHA plus D3: PRN De3.
- Two-capsule rTG formula: I-VU Omega-3 Plus.
- Omega-3 plus GLA: NutraSea Dry Eye.
- Simple triglyceride EPA/DHA formula: Systane Omega-3.
- One capsule without listed EPA/DHA: Blink NutriTears.
Fair-comparison rule: This table compares formulas, not guaranteed outcomes. There are no robust head-to-head trials proving PRN De3 clinically outperforms all four products.
Frequently asked questions
Is PRN De3 worth the premium?
It offers the highest EPA+DHA dose in this comparison, rTG form, vitamin D3 and unusually specific Canadian dry-eye claims. Whether those differences justify the price depends on response, budget and professional advice.
Which has the fewest capsules?
Blink uses one daily but is not an omega-3 formula. Among compared omega products, I-VU uses two; PRN and Systane use three; NutraSea uses four.
Can I combine two products?
Do not stack them without reviewing total EPA, DHA, vitamin D and bleeding risk with a pharmacist or physician.
Compare Canadian dry-eye supplements
Shop eye vitamins and omega-3s
Shop eye vitamins and omega-3s
Sources
- Current EyeDropShop Canada product pages for PRN De3, I-VU Omega-3 Plus, NutraSea Dry Eye Soft Gels, Systane Omega-3 and Blink NutriTears, accessed July 2026.
- Health Canada NPN 80101489
- Epitropoulos et al., 2016
Product details may change. Check the current Canadian label and consult a healthcare professional.
